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D dose-ranging comparisons in the bactericidal and sterilizing routines of rifampin and rifapentine, alone and together with isoniazid and pyrazinamide with or with out ethambutol, in BALB/c mice and in C3HeB/FeJ mice, which acquire necrotic lung granulomas after an infection with Mycobacterium tuberculosis are performed.Histamine played an essenti